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Jack of All Trades

There is a commonly misquoted phrase that says, “A jack of all trades is a master of none.” However, the full quote attributed to William Shakespeare actually reads, “A jack of all trades is a master of none, but often times better than a master of one.”

Possessing skills in multiple areas is valuable. Today it is even more valuable than in the past.  Learning even a little bit about business, philosophy, physics, coding, economics, gardening, ranching, construction, etc. may put you in a position of immediate value in almost any group.

Become a T-shaped person.  This is a person who has specialized knowledge and skills in a particular area, as well as the desire and ability to make connections across different disciplines. 

I have personally found that expanding my learning in other broad areas of interest have made my expertise in medicine, health and diet so much more rewarding. It is why I have my own ranch with horses, goats, chickens, ducks and dogs. It is why I’ve studied European Swordsmanship and Martial Arts. It was the driver for getting trained in hypnotherapy. And, it is why I love riding motorcycles. All of these interests have played a role in deepening my medical expertise.

“Like chess masters and firefighters, pre-modern villagers relied on things being the same tomorrow as they were yesterday. They were extremely well prepared for what they had experienced before, and extremely poorly equipped for everything else. Their very thinking was highly specialized in a manner that the modern world has been telling us is increasingly obsolete. They were perfectly capable of learning from experience, but failed at learning without experience.

“And, that is what a rapidly changing, wicked world demands, conceptual reasoning skills that can connect new ideas and work across contexts. Faced with any problem they had not directly experienced before, the remote villagers were completely lost.

“That is not an option for us. The more constrained and repetitive a challenge, the more likely it will be automated, while great rewards will accrue to those who can take conceptual knowledge from one problem or domain and apply it in an entirely new one” (David Epstein, Range: Why Generalists Triumph in a Specialized World).

It is possible that in an earlier world, where change occurs slowly, specialization represents and provides a significant competitive advantage. However, in today’s ever-changing world, integrating your specialist skills with a variety of other skills becomes a new and powerful competitive advantage.

In a world where you have the freedom to explore the things you’re curious about, don’t limit yourself to just one. Definitely be an expert in one particular field, but don’t be afraid to go out and learn about topics that aren’t directly related to your specialty.

“A jack of all trades is a master of none, but oftentimes better than a master of one.”

Living With Pandemics and Potential Nuclear Warfare

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[Adapted from “On Living In An Atomic Age (1948), by C.S. Lewis]

Too many of us spend way too much time thinking about the global pandemic, economic collapse and nuclear war.

“How are we to live in this era of nuclear threat, escalating inflation and rampant viruses?”

I am often tempted to reply, “The same way you would have lived in the early twentieth century when the great depression hit, or like you would have lived in the sixteenth century when the plague visited London almost every year, or as you would have lived in a Viking age when raiders from Scandinavia might land and cut your throat any night; or indeed, as you are already living in an age of cancer, an age of tuberculosis, an age of paralyzing polio, an age of syphilis, an age of air raids, and age of railway accidents or an age of motor vehicle accidents.

In other words, don’t begin by exaggerating the novelty of our situation. Believe me, you and everyone you love have already been sentenced to death before the threat of viral pandemics or nuclear warfare was ever invented: and a high percentage of use were going to die in unpleasant ways.  You and I have a great advantage over our ancestors – antibiotics and anesthetics – to this day we still have them.

It is perfectly ridiculous to go whimpering about the day with long drawn faces because the great scientists of our time have added one more chance of a painful and premature death to a world which already bristled with such chances and in which death itself was not a chance at all, but a certainty.  None of us get out of this alive.  None.  Not one.

My first point in this monologue is that you and I must pull ourselves together.  If we are all going to be destroyed by a virus, skyrocketing inflation or a nuclear bomb, then let that destruction, when it comes, find us doing sensible human things like praying, working, teaching, reading, listening to music, bathing the children, playing golf (scratch that – I hate golf), chatting to our friends over a pint and a game of chess or darts – not huddled together like frightened sheep, thinking about viruses or nuclear warfare or gasoline prices.  They may break our bodies (in my experience, any microbe can do that) but, they need not dominate our minds.

“But,” you will reply, “it is not death – not even painful and premature death – that we are all hot and bothered about.  Of course, the chance of that is not a new thing.  What is new is that the virus or the bomb or climate change may finally and totally destroy civilization itself.  The lights may be put out forever.”

This brings us much nearer to the real point.  Let me try to make clear exactly what I think that point is.  What were your views about the ultimate future of civilization before the pandemic appeared on the scene? What did you think all this effort of humanity was to come to in the end?   The real answer is clear to almost everyone who has even a smidgeon of scientific background; yet, oddly enough, it is hardly ever mentioned.  And the real answer (almost beyond doubt) is that with or without viruses, nuclear warfare and economic collapses the whole story is going to end in NOTHING.

The astronomers hold out no hope that this plant is going to be permanently inhabitable. The physicists hold out no hope that organic life is going to be a permanent possibility in any part of the material universe. Not only this earth, but the whole show, all the suns of space, are to run down. Nature is a sinking ship, and we are but passengers.

Nature does not, in the long run, favor life. If Nature is all that exists — in other words, if there is no God, and no after-life of some sort somewhere outside Nature — then all stories will end in the same way: in a universe from which all life is banished without any possibility of return. It will have been an accidental flicker, and there will be no one even to remember it.

No doubt a nuclear bomb may cut its duration on this present planet shorter that it might have been; but the whole thing, even if it lasted for billions of years, must be so infinitesimally short in relation to the oceans of dead time which preceded and follow it that I really feel no excitement about its curtailment.

What the wars and the weather and the pandemic have really done is to remind us forcibly of the sort of world we are living in and which, during the prosperous periods before 1914 and 2021, we began to forget.  And, in reality, this reminder is actually a good thing.  We have been awakened from a pretty dream, and now we can begin to talk about reality.

We see at once (when we have been waked, no “woke”) that the important question is not whether a virus or a nuclear weapon is going to obliterate our “civilization.” The important question is whether “Nature” — the thing studied by the sciences – is the only thing in existence? Because if you answer yes to the second question, then the first question only amounts to asking whether the inevitable frustration of all human activities may be hurried on by our own action instead of occurring at its own natural time. That is, of course, a question that concerns us very much.

Even on a leaking ship that is known to certainly sink sooner or later, the news that the boiler might blow up now would not be heard with indifference by anyone.  But those who knew the ship was sinking in any case would not, I think, be quite so desperately excited as those who had forgotten this fact, and were vaguely imagining that it might arrive somewhere.

It is, then, on this second question that you and I really need to make up our minds.

Let us begin by supposing that Nature is all that exists. Let us suppose that nothing ever has existed or ever will exist before or after except this meaningless play of atoms in space and time: that by a series of hundredth changes it has (regrettably) produced things like — conscious beings who now know that their own consciousness is an accidental result of the whole meaningless process and is therefore itself meaningless – though to us, it feels quite significant.

In this situation (in which the Oxford Handbook estimates 25-50% of civilized countries seems to believe is the present reality), there are really only three avenues of action:

(1) You might commit suicide. Nature which has blindly & accidentally given me for my torment this consciousness which demands meaning and value in a universe that offers neither, has luckily also given me the means of getting rid of it. I return the unwelcome gift. I will be fooled no longer.  (I do not recommend this avenue.)

(2) You might decide simply to have as good a time as possible. The universe is a universe of nonsense, but since you are here, grab what you can. Unfortunately, however, there is on these terms, with inflation and gasoline prices so high so very little left to grab — only the coarsest sensual pleasures is really left. You can’t, except in the lowest animal sense, be in love with a girl if you know (and keep on remembering) that all the beauties both of her person, and of her character, are a momentary and accidental pattern produced by the collision of atoms, and that your own response to them is only a sort of psychic phosphorescence arising from the behavior of your genes.

You can’t go on getting any very serious pleasure from music if you know and remember that its air of significance is a pure illusion, that you like it only because your nervous system is irrationally conditioned to like it.

You may still, in the lowest sense, have a “good time”; but just in so far as it becomes very good, just in so far as it ever threatens to push you on from cold sensuality into real warmth and enthusiasm and joy, so far you will be forced to feel the hopeless disharmony between your own emotions and the universe in which you really live.

3) You may defy the universe. You may say, “Let Nature be irrational, I am not. Let it be merciless, I will have mercy. By whatever curious chance it has produced me, now that I am here, I will live according to human values. I know the universe will win in the end, but what is that to me? I will go down fighting. Amid all this wastefulness I will persevere; amid all this competition, I will make sacrifices. Be damned to the universe!”

I suppose that most of us, in fact, while remain materialists, adopt a more or less uneasy alternate position between the second and the third attitude. And although the third is incomparably the better (it is, for instance, much more likely to “preserve civilization”), both really end up shipwrecked on the same rock. That rock — disharmony between our own hearts and Nature — the is obvious in the second. The third seems to avoid the rock by accepting disharmony from the outset and defying it. Yet, it won’t really work. In it, you hold up your own human standards against the idiocy of the universe.

That is, we talk as if our own standards were something outside the universe which can be contrasted with it; as if we could judge the universe by some standard borrowed from another supposed realistic source). But if Nature — in the space–time–matter system — is the only thing in existence, then of course there can be no other source for our standards. They must, like everything else, be the unintended and meaningless outcome of blind forces. Far from being a light from beyond Nature whereby Nature can be judged, they become the only the way in which anthropoids of our species feel when the atoms under our own skulls get into certain states — those states being produced by causes quite irrational, unhuman, and non-moral. Thus, the very ground on which we defy Nature crumbles under our feet. The standard we are applying is tainted at the source. If our standards are derived from this meaningless universe they must be as meaningless as Nature.

For most modern people, thoughts of this kind must be thought through before the opposite view can even get a fair hearing. All Naturalism leads us to this in the end — to a quite final and hopeless discord between what our minds claim to be and what they really must be if Naturalism is true. They claim to be spirit; that is, to be reason, perceiving universal intellectual principles and universal moral laws and possessing free will. But if Naturalism is true, they must in reality be merely arrangements of atoms in skulls, coming about by irrational causation. We never think a thought because it i s true, only because blind Nature forces us to think it. We never do an act because it is right, only because blind Nature forces us to do it. It is when one has faced this preposterous conclusion that one is at last ready to listen to the voice that whispers: “But suppose we really are spirits? Suppose we are not the offspring of Nature . . ?”

For, really, the naturalistic conclusion is unbelievable. For one thing, it is only through trusting our own minds that we have come to know Nature itself. If Nature when fully known seems to teach us (that is – if the sciences teach us) that our own minds are chance arrangements of atoms, then there must have been some mistake; for if that were so, then the sciences themselves would be chance arrangements of atoms and we should have no reason for believing in them.

There is only one way to avoid this deadlock. We must go back to a much earlier view. We must simply accept it that we are spirits, free and rational beings, at present inhabiting an irrational universe, and must draw the conclusion that we are not derived from it. We are strangers here. We come from somewhere else. Nature is not the only thing that exists. There is “another world,” and that is where we come from. And that explains why we do not feel at home here.

A fish feels at home in the water. If we “belonged here” we should feel at home here. All that we say about “Nature,” about death and time and mutability, all our half-amused, half-bashful attitude to our own bodies, is inexplicable on the theory that we are simply natural creatures. If this world is the only world, how did we come to find its laws either so dreadful or so comic? If there is no straight line elsewhere, how did we discover that Nature’s line is crooked?

But what, then, is Nature, and how do we come to be imprisoned in a system so alien to us?

Oddly enough, the question becomes much less sinister the moment one realizes that Nature is not the end all be all. Mistaken for our mother, she is terrifying and even abominable. But if she is only our sister — if she and we have a common Creator — if she is our sparring partner — then the situation suddenly becomes quite tolerable.

Perhaps we are not here as prisoners but as colonists: only consider what we have done already to the dog, the horse, or the daffodil. Nature is indeed a rough playfellow. There are elements of evil in her. To explain all that would carry us far back: I should have to speak of Power and Principalities and all that would seem to the modern reader most mythological. This is not the place, nor do these questions come first.

It is enough to say here that Nature, in her different way, is much alienated from her Creator, though in her, as in us, gleams and rays of the old beauty remain. Yet, they are there not to be worshipped, but to be enjoyed. She has nothing to teach us. It is our business to live by our own law, not by hers: to follow, in private or in public life, the law of love and temperance even when they seem to be suicidal, and not the law of competition and grab, even when they seem to be necessary to our survival. For it is part of our spiritual law never to put survival first: not even the survival of our species. We must resolutely train ourselves to feel that the survival of Man on this Earth, much more of our own nation or culture of class, is not worth having unless it can be had by honorable and merciful means.

The sacrifice is not so great as it seems. Nothing is more likely to destroy a species or a nation than a determination to survive at all costs. Those who care for something else more than civilization are the only people by whom civilization is at all likely to be preserved. Those who want Heaven must have served Earth best. Those who love Man less than God do most for Man.

Smoked Pork Shoulder & 12 Essentials About Bacon

A number of people have asked me about how I smoke my pork shoulders.  Pork shoulder is a perfect meal if you are on a ketogenic or carnivorous diet.   The smoking process is quite simple.  The key is in the simplicity.  I’ve use a Traeger Select Elite pellet smoker for the last 10 years, but your favorite smoker will do.

In our house, we will smoke a 9-10 lbs pork shoulder and then use the pulled pork for meals throughout the week.  I often do most of my smoking on the weekend when I am home and then we have some of the most tasty leftovers throughout the week.

But, before I dive into the recipe and process, we should take a moment to look at the historical essentials of bacon and it’s origins from the pork shoulder.

Bacon Dates Back to 1500 BC

The Chinese were the first to record cooking of salted pork bellies more than 3000 years ago.  This makes bacon one of the world’s oldest processed meats.

Romans Called It “PETASO

Bacon eventually migrated westward where it became a dish worth of modern-day foodies.  The Romans made petaso, as they called it, by boiling salted pig shoulder with figs, then seasoning the mixture with pepper sauce.  Wine was, of course, a frequent accompaniment.  For my wine connoisseur friends, please tell me which wine goes best with bacon. . . you know who you are.

The Word Refers to the “Back” of a Pig

The word bacon  comes from the Germanic root “-bak,” and refers to the back of the pig that supplied the meat.  Bakko become the French bacco, which the English then adopted around the 12th century, naming the dish bacoun.  Back then, the term referred to any pork product, but by the 14th century bacoun referred specifically to the cured meat.

The First Bacon Factory Opened in 1770

For generations, local farmers and butchers made bacon for their local communities.  In England. where it became a dietary staple, bacon was typically “dry cured” with salt and then smoked.  In the late 18th century, a businessman named John Harris opened the first bacon processing plant in the county of Wiltshire, where he developed a special brining solution for finishing the meat.  The “Wilshire Cure” method is still used today, and is a favorite of bacon lovers who prefer a sweeter, less salty taste.

“Bringing Home The Bacon” Goes Back Centuries

These days, the phrase refers to making money, but it’s origins have nothing to do with income.  In 12th century England, churches would award a “flitch,” or a side, of bacon to any married man who swore before God that he and his wife had not argued for a year and a day.  Men who “brought home the bacon” were seen as exemplary citizens and husbands.

Bacon Helped Make Explosives During World War II

In addition to planting victory gardens and buying war bonds, households were encouraged to donate their leftover bacon grease to the war effort. Rendered fats created glycerin, which in turn created bombs, gunpowder, and other munitions. A promotional film starring Minnie Mouse and Pluto chided housewives for throwing out more than 2 billion pounds of grease every year: “That’s enough glycerin for 10 billion rapid-fire cannon shells.”

Hardee’s Frisco Burger Was a Game Changer for Bacon

Bacon took a beating in the 1980s, when dieting trends took aim at saturated fats and cholesterol. By the ’90s, though, Americans were ready to indulge again. Hardee’s Frisco Burger, one of the first fast-food burgers served with bacon, came out in 1992 and was a hit. It revived bacon as an ingredient, and convinced other fast-food companies to bacon-ize their burgers. Bloomberg called it “a momentous event for fast food, and bacon’s fate, in America.”

The Average American Consumes 18 lbs of Bacon Each Year

Savory, salty, and appropriately retro: The past couple years have been a bonanza for bacon, with more than three quarters of restaurants now serving bacon dishes, and everything from candy canes to gumballs now flavored with bacon. Recent reports linking processed meats to increased cancer risk have put a dent in consumption, and may have a prolonged effect. But for now, America’s love affair with bacon continues.

There is a Church of Bacon

This officially sanctioned church boasts 13,000 members under the commandment “Praise Bacon.” It’s more a rallying point for atheists and skeptics than for bacon lovers, per se, and there’s no official location as of yet. But the church does perform wedding ceremonies and fundraisers, and has raised thousands of dollars for charity. All bacon praise is welcome, even if you’re partial to vegetarian or turkey bacon over the traditional pork. Hallelujah!

There is a Bacon Camp

It’s like summer camp, but with less canoeing and more bacon cooking. Held every year in Ann Arbor, Michigan, Camp Bacon features speakers, cooking classes, and other bacon-related activities for chefs and enthusiasts eager to learn more about their favorite food.

Modern Technology Wants to Help You Wake Up and Smell the Bacon

An ingenious combination of toaster and alarm clock, the Wake ‘n Bacon made waves a few years back with the promise of waking up to fresh-cooked bacon. Sadly, the product never made it past the prototype phase, but those intent on rising to that smoky, savory aroma were able to pick up Oscar Mayer’s special app, which came with a scent-emitting attachment.

There Is A Bacon Sculpture of Kevin Bacon

It had to happen eventually. Artist Mike Lahue used seven bottles of bacon bits, lots of glue, and five coats of lacquer to create a bust of the Footloose star, which sold at auction a few years back. No word on how well the bacon bit Bacon bust has held up.
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Dr. Nally’s Smoked Pork Shoulder

Apply dry rub liberally to all sides of the pork shoulder 30-60 minutes before putting the shoulder onto the smoker using the following dry spices:
Refrigerate the pork shoulder after applying dry rub until ready to place on the smoker.
Preheat smoker to 250˚F degrees and place the pork shoulder fat side up onto the grill.  Smoke it until internal temperature reaches 150-160˚F.

To Wrap Or Not To Wrap?

I wrap my pork shoulders in two layers of foil, to better seal in flavor and juiciness. I don’t wrap my briskets (unless I plan on storing them for later use).

Once the meat gets to around 160° internal temp (around the four to five hour mark) is the perfect time to wrap. Your pork shoulder should have excellent color and bark at this point.

Wrap the pork up in foil and place it back on the smoker, making sure you keep your temp probe in and wrap the foil around it.  Once it is wrapped, place it fat side up and continue to smoke it at 250˚F until it reaches an internal temperature of 205˚F.

How Long Does It Take to Smoke a Pork Shoulder?

Smoking time averages 60-90 minutes per pound, depending on the level of doneness smoked at 250 degrees.

If you’re going to slice it, cook to 185˚F.

If your going to pull the pork smoke it longer, until it reaches 205˚F.

 

Why Do You Do That Sword Fighting Thing?

I was asked, recently, by a friend, “Why do you do that sword fighting thing?”

As I’ve pondered this question, I found my answer in the words of Jack Donovan.

“Strength, courage, mastery, and honor are the alpha virtues of men all over the world. They are the fundamental virtues of men because without them, no “higher” virtues can be entertained. You need to be alive to philosophize. You can add to these virtues and you can create rules and moral codes to govern them, but if you remove them from the equation altogether you aren’t just leaving behind the virtues that are specific to men, you are abandoning the virtues that make civilization possible.

“Plato at one point in time compared men to dogs. One of the great tragedies of modernity is the lack of opportunity for men to become what they are, to do what they were bred to do, what their bodies want to do. They could be Plato’s noble puppies, but they are chained to a stake in the ground—left to the madness of barking at shadows in the night, taunted by passing challenges left unresolved and whose outcomes will forever be unknown.

“If you are never truly challenged in a meaningful way and are only required to perform idiot-proofed corporate processes to get your meat and shelter, can you ever truly be engaged enough to call yourself alive, let alone a man?

“Men cannot be men—much less good or heroic men—unless their actions have meaningful consequences to people they truly care about. Strength requires an opposing force, courage requires risk, mastery requires hard work, honor requires accountability to other men. Without these things, we are little more than boys playing at being men, and there is no weekend retreat or mantra or half-assed rite of passage that can change that. A rite of passage must reflect a real change in status and responsibility for it to be anything more than theater. No reimagined manhood of convenience can hold its head high so long as the earth remains the tomb of our ancestors”

Sword fighting encompasses it all.

I’ve come to realize that training with the sword, against other men, fulfills a masculine yearning and desire I’ve felt for over 50 years.  Why would God include hundreds of chapters of wars and sword fights in the scriptures? Because, the nobility of prophets and kings, their strength, courage, mastery and honor, was often forged at the hilt of a sword.

That’s why I sword fight.

Watch the video below and you can see where sword fighting provides the repeated opposing force, risk, hard work and accountability that are prerequisites of success.  Sword fighting is really just rapid short and very exciting lessons on life.

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I hope you enjoy watching as much as I enjoyed participating.

 

High Fat? High Protein? Low Protein? What is really ketogenic?

The daily question that I get asked by my patients, and from those around the internet, relates to burning one’s own fat. “Don’t you have to limit the calories and limit fat you eat to burn your own body fat?

It seems everyone has a differing opinion on this question and a few of them have two opinions (you know who you are).  Very few of these opinions are grounded in the actual science of weight loss.

I hear coaches, trainers and even a number physicians argue, name call and rant about the need to cut calories to lose fat.  Yet, most of my patients “cut their calories” 200-1000 per day without successful fat reduction.  They may increase their exercise by 400-600 calories per day and still no weight loss.  This is the same crazy ineffective instruction we’ve been given for the last 50 years.

To be honest, there is a percentage of those in the fitness and modeling worlds upon which this dogma is effective and that is because of normal insulin levels and significant exercise. However, for the other 85% of the world who work over 40-80 hours a week, have children and families, serve in our churches and occasionally have a social life, myself included, it doesn’t work.  If we were all paid to exercise 2 hours a day and take “butt selfies” on Instagram, it might be easier.

Yes, you will probably lose 20 lbs. with calorie restriction, but your testosterone will drop by up to 50%, sex hormone binding globulin will double, and over time your basal metabolic rate will slow due to dramatic and often permeant reduction in thyroid function.  This makes it nearly impossible to lose more than that 20 lbs, and then you will regain the weight once calorie levels return to normal within 18-24 months.  (No one ever talks about that little problem, do they?)

For those of you that want to see success in weight loss, let’s outline a few essential principles that the trainers, keto-coaches and social media talking heads aren’t mentioning.

First, insulin has to be kept at a baseline.  The reason that 85% of people don’t, won’t and can’t see effective weight loss beyond 20-30 lbs long term (greater than 2 years) with calorie restriction is that 85% of the population has some degree of insulin resistance.  It’s not a disease, it’s a syndrome associated with the effect of the standard American diet.  I wrote a whole book about it called The Keto Cure.  We know that insulin and catecholamines increase the rate by which fat is stored.

Second, glucacon is a counter active hormone to keep your blood sugar from bottoming out.  The presence of glucagon stimulates fat burningIntermittent fasting and ketogenic dietary intake allow blood sugar to drop below 70 mg/dL (3.9 mmol/L) causing glucagon release and stimulate increased release of free fatty acids from the fat cells.

Third, two hormones, epinephrine and norepinephrine, are produced when blood sugar drops below 67 mg/dL (3.7 mmol/L).  Exercise lowers blood sugar to this level and stimulates additional burning of fat by engaging the release of glucagon and epinephrine and norepinephrine.  Exercise, also, has three other myokine hormonal effects making weight loss more successful when the diet is correctly balanced.

The fourth principle that is essential to understand relates to growth hormone.  Growth hormone stimulates and preserves muscle tissue, has a suppressive effect on insulin. Growth hormone increases with exercise, sleep, intermittent fasting and when protein intake is at least greater than 90 grams per day in women and around 1 gram of protein per body weight in men.  This is notably higher than previous calculations on protein that I have written about in the past.  Recent research, also found here, here and here, demonstrates that increased protein above 90-100 grams per day enhances muscle growth and stabilization and further suppresses insulin production beyond what we previously understood.
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Contrary to what the media has been saying about protein sources, not all protein is absorbed in the same way.  When it comes to absorption in the human gut and use by the human metabolism, protein sources differ in their effectiveness:

    • Egg protein utilization – 50%
    • Meat protein utilization – 40%
    • Cheese protein utilization 35-40%
    • Whey protein utilization – 18%
    • Vegetable protein utilization – 14%

Lastly, release of fat from the fat cell is mediated by natriuretic peptides and cGMP through the release of catecholamines, prostaglandins and nicotinic acid.  Interestingly, the major positive regulators of human lipolysis are catecholamines and natriuretic peptides (NPs). Fatty acid release from fat cells triples when catecholamines and natriuretic peptides are released.  Catecholamines are produced by exercise, stimulants and stress, and natriuretic peptides are stimulated by short change fatty acids (ketones).

For the science geeks in who follow my blog, I’ve included the following picture that summarizes the effects of these hormones on the fat cell.  The figure below shows the major pathways by which insulin, thyroid, catecholamines, testosterone and sympathomimetics effect fatty acid release from adipose tissue.

Primary signaling pathways in human lipolysis. Black and red lines indicate pro-lipolytic and anti-lipolytic signaling events, respectively. Arrows indicate stimulation and/or translocation and blunt lines indicate inhibition. Stimulation of lipolysis is dependent on PKA- or PKG-mediated phosphorylation of HSL and PLIN1. PKG is activated by cGMP, which is increased in response to activation of the GC-coupled NPR-A. Similarly, stimulation of the Gs-protein-coupled β1/2-ARs activates AC, which generates cAMP and activates PKA. Conversely, activation of Gi-protein-coupled α2-ARs inhibits AC and thereby reduces cAMP-dependent signaling to lipolysis. Stimulation of the insulin signaling pathway through the IR increases the activity of PDE3B, which converts cAMP to 5′-AMP, thus decreasing PKA activity and suppressing lipolysis. PKG activity is reduced by PDE5-mediated conversion of cGMP to 5′-GMP, although the upstream signals regulating this process are currently unknown. The dashed line indicates a putative Akt-independent insulin pathway acting selectively on PLIN1. α2-ARs, α2-adrenergic receptors; AC, adenylyl cyclase; TG, triglyceride; ATGL, adipose TG lipase; β1/2-ARs, β1- and β2-adrenergic receptors; CGI-58, comparative gene identification-58; DG, diacylglycerol; FFA, free fatty acid; GC, guanylyl cyclase; HSL, hormone-sensitive lipase; IR, insulin receptor; IRS1/2, IR substrates 1 and 2; MG, monoacylglycerol; MGL, monoglyceride lipase; NPR-A, type-A natriuretic peptide receptor; PDE3B, phosphodiesterase 3B; PDK, phosphoinositide-dependent kinase; PI3K, phosphatidylinositol 3-kinase; PKA, protein kinase A; PKB/Akt, protein kinase B; PLIN1, perilipin 1. (Journal of Molecular Endocrinology 52, 3; 10.1530/JME-13-0277)

The take home message from this information is this, effective long term weight loss cannot be achieved by calorie restriction.  Effective weight loss (specifically fat loss and muscle gain) is most effectively achieved when carbohydrates are restricted, protein is optimized, and proper exercise adequately triggers the release of fat burning hormones.

Click HERE and get a copy of my ketogenic diet.

Get a copy of my diet and 13 learning modules with coaching and online assistance by becoming a member of Dr. Nally’s KetoClan.

I’d like to know, what combination has been most effective for you?

Have a great day!

Adam (eat your bacon) Nally, DO